Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.48 |
| ▸ | MLNR | O43193 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29309518 | 0.97 | HRH2 (0.51) | CHRM1CHRM3MLNRNR1I2PGR | |
| SCHEMBL18893188 | 0.92 | CHRM1 (0.48) | CHRM1CHRM3MLNRNR1I2PGR | |
| SCHEMBL101410 | 0.89 | MLNR (0.47) | CHRM1CHRM3MLNRNR1I2PGR | |
| SCHEMBL18876746 | 0.89 | MLNR (0.47) | CHRM1CHRM3MLNRNR1I2PGR | |
| SCHEMBL101398 | 0.87 | MLNR (0.51) | CHRM1CHRM3MLNRNR1I2PGR | |
| SCHEMBL29309516 | 0.86 | MLNR (0.51) | CHRM1CHRM3MLNRNR1I2PGR | |
| SCHEMBL19975739 | 0.86 | MLNR (0.51) | CHRM1CHRM3MLNRNR1I2PGR | |
| SCHEMBL19975740 | 0.84 | HRH2 (0.54) | CHRM1CHRM3MLNRNR1I2PGR | |
| SCHEMBL101509 | 0.84 | PTPN1 (0.55) | CHRM1CHRM3MLNRNR1I2PGR | |
| SCHEMBL18876747 | 0.84 | FOLH1 (0.43) | CHRM1CHRM3MLNRNR1I2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170145502-A1 | MODIFIED NUCLEOTIDE REAGENTS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2017-05-25 | — | — | US | disclosed |
| US-20170145496-A1 | LABELED NUCLEOTIDE ANALOGS, REACTION MIXTURES, AND METHODS AND SYSTEMS FOR SEQUENCING | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2017-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170145496-A1 | LABELED NUCLEOTIDE ANALOGS, REACTION MIXTURES, AND METHODS AND SYSTEMS FOR SEQUENCING | POLL, POLN, POLB | CHRM1 4622/4885CHRM3 4295/4885MLNR 1617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.