SCHEMBL18876887

SCHEMBL18876887

c1ccc(-c2cccc(-c3nc(-c4cccc(-n5c6ccc7ccccc7c6c6c7ccccc7ccc65)c4)nc4ccccc34)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
ATM Q13315 1/20 0.40
PDE10A Q9Y233 2/20 0.37
ABCG2 Q9UNQ0 4/20 0.36
ADORA2A P29274 3/20 0.36
WHR1 P49842 1/20 0.36
GAA P10253 1/20 0.36
NR1I3 Q14994 3/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
VDR P11473 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2B6 P20813 1/20 0.34
AHR P35869 1/20 0.34
NPC1 O15118 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
RECQL P46063 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18876899 0.99 MEN1 (0.42) MEN1KMT2AATMPDE10AABCG2
SCHEMBL18876905 0.97 MEN1 (0.45) MEN1KMT2AATMPDE10AABCG2
SCHEMBL18876884 0.95 MEN1 (0.40) MEN1KMT2AATMPDE10AABCG2
SCHEMBL18876902 0.94 MEN1 (0.45) MEN1KMT2AATMPDE10AABCG2
SCHEMBL18876900 0.94 MEN1 (0.47) MEN1KMT2AATMPDE10AABCG2
SCHEMBL18876903 0.94 MEN1 (0.47) MEN1KMT2AATMPDE10AABCG2
SCHEMBL18876901 0.94 MEN1 (0.46) MEN1KMT2AATMABCG2ADORA2A
SCHEMBL20315516 0.92 MEN1 (0.41) MEN1KMT2AATMPDE10AABCG2
SCHEMBL20315532 0.92 MEN1 (0.41) MEN1KMT2AATMPDE10AABCG2
SCHEMBL17533326 0.92 MEN1 (0.42) MEN1KMT2AATMABCG2ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10186669-B2 Organic electroluminescent compound and an organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD (KR) 2019-01-22 US disclosed
US-9997723-B2 Organic electroluminescent compound and an organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD (KR) 2018-06-12 US disclosed
US-9997723-B2 Organic electroluminescent compound and an organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD (KR) 2018-06-12 US disclosed
US-20170279056-A1 A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-09-28 US disclosed
US-20170279056-A1 A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-09-28 US disclosed
US-20170148998-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND AN ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-05-25 US disclosed
US-20170148998-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND AN ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10186669-B2 Organic electroluminescent compound and an organic electroluminescent device comprising the same OR10J3, OPA1, ODC1 MEN1 2000/4885KMT2A 2048/4885ATM 3570/4885
US-20170148998-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND AN ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, OPA1, ODC1 MEN1 2000/4885KMT2A 2048/4885ATM 3570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.