Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2608445 | 0.82 | KDM5B (0.34) | PLAUELANE | |
| SCHEMBL22022298 | 0.78 | SCN5A (0.30) | PLAUELANE | |
| SCHEMBL25452956 | 0.78 | SCN5A (0.30) | PLAUELANE | |
| SCHEMBL25666521 | 0.75 | — | — | |
| SCHEMBL19431216 | 0.74 | NPC1 (0.31) | — | |
| SCHEMBL17083377 | 0.74 | PLAU (0.34) | PLAUELANE | |
| SCHEMBL12019737 | 0.74 | KIT (0.43) | PLAUELANE | |
| SCHEMBL19346310 | 0.73 | PLAU (0.32) | PLAUELANE | |
| SCHEMBL22951252 | 0.72 | KCNN4 (0.35) | PLAUELANE | |
| SCHEMBL17109830 | 0.72 | PDK2 (0.37) | PLAUELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9738644-B2 | Chemical compounds, compositions and methods for kinase modulation | INFINITY PHARMACEUTICALS, INC. (US) | 2017-08-22 | — | — | US | disclosed |
| US-9655892-B2 | Certain chemical entities, compositions and methods | INTELLIKINE LLC (US) | 2017-05-23 | — | — | US | disclosed |