⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL887442 | 0.50 | — | — | |
| SCHEMBL5640 | 0.47 | — | — | |
| SCHEMBL15869348 | 0.47 | — | — | |
| SCHEMBL10417889 | 0.47 | — | — | |
| Iodide SCHEMBL377678 | 0.41 | — | — | |
| Ammonia Solution, Strong SCHEMBL4138673 | 0.41 | — | — | |
| SCHEMBL5859282 | 0.41 | — | — | |
| SCHEMBL5383540 | 0.41 | — | — | |
| SCHEMBL10275116 | 0.41 | — | — | |
| Hydrogen Sulfide SCHEMBL5192038 | 0.41 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170145058-A1 | METHOD FOR TARGETED CONJUGATION OF PEPTIDES AND PROTEINS BY PAIRED C2 BRIDGING OF CYSTEINE AMINO ACIDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-05-25 | — | — | US | disclosed |
| US-20140065153-A1 | Methods for Treating Hair Loss Disorders | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-03-06 | — | — | US | disclosed |
| US-8653286-B2 | Intermediates useful in the preparation of maleimide functionalized polymers | NEKTAR THERAPEUTICS (US) | 2014-02-18 | — | — | US | disclosed |
| US-8653131-B2 | Polymeric benzyl carbonate-derivatives | BAXTER HEALTHCARE S.A. (CH) | 2014-02-18 | — | — | US | disclosed |
| US-20140045770-A1 | OLIGOMER-PROTEASE INHIBITOR CONJUGATES | NEKTAR THERAPEUTICS (US) | 2014-02-13 | — | — | US | disclosed |
| US-20140039205-A1 | Method for Preparing Branched Functionalized Polymers Using Branched Polyol Cores | NEKTAR THERAPEUTICS (US) | 2014-02-06 | — | — | US | disclosed |
| US-20140017198-A1 | INHIBITORS OF HEPATITIS C VIRUS | GILEAD PHARMASSET LLC | 2014-01-16 | — | — | US | disclosed |
| US-20130303531-A1 | TETRA-SUBSTITUTED NDGA DERIVATIVES VIA ETHER BONDS AND CARBAMATE BONDS AND THEIR SYNTHESIS AND PHARMACEUTICAL USE | CHEN QINGQI (US) | 2013-11-14 | — | — | US | disclosed |
| US-8568705-B2 | Method for preparing branched functionalized polymers using branched polyol cores | NEKTAR THERAPEUTICS (US) | 2013-10-29 | — | — | US | disclosed |
| US-20130280700-A1 | FOUR-COLOR DNA SEQUENCING BY SYNTHESIS USING CLEAVABLE FLUORESCENT NUCLEOTIDE REVERSIBLE TERMINATORS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2013-10-24 | — | — | US | disclosed |
| US-20080064851-A1 | Active carbonate esters of water-soluble polyoxyethylene glycol | NEKTAR THERAPEUTICS | 2008-03-13 | — | — | US | disclosed |
| US-20080039656-A1 | Synthesis and Application of Procainamide Analogs for Use in an Immunoassay | DADE BEHRING INC. (US) | 2008-02-14 | — | — | US | disclosed |
| US-20070299073-A1 | Imidazolyl derivatives | IPSEN PHARMA S.A.S. (FR) | 2007-12-27 | — | — | US | disclosed |
| US-7279340-B2 | Synthesis and application of procainamide analogs for use in an immunoassay | DADE BEHRING INC. (US) | 2007-10-09 | — | — | US | disclosed |
| US-7238695-B2 | Imidazolyl derivatives | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, SAS (FR) | 2007-07-03 | — | — | US | disclosed |
| US-20070117102-A1 | Nucleotide analogs | FLUIDIGM CORPORATION | 2007-05-24 | — | — | US | disclosed |
| US-7217575-B2 | Avidin derivatives and uses thereof | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2007-05-15 | — | — | US | disclosed |
| US-20070032653-A1 | N-{1-(4-(3-bromophenyl)-1H-imidazol-2-yl)-5-methylhexyl}-N-cyclohexylamine; agonists or antagonists of somatostatin receptors; acromegaly, restenosis, Crohn's disease, systemic sclerosis, external and internal pancreatic pseudocysts and ascites, nesidoblastosis, hyperinsulinism, gastrinoma, etc. | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) | 2007-02-08 | — | — | US | disclosed |
| US-20070031371-A1 | Method for Preparing Branched Functionalized Polymers Using Branched Polyol Cores | NEKTAR THERAPEUTICS AL, CORPORATION | 2007-02-08 | — | — | US | disclosed |
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |