Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | DDR1 | Q08345 | 4/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.40 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18890852 | 0.95 | KDM4D (0.42) | DDR1PDE4BPDE11APDE10AKDM4D | |
| SCHEMBL18864042 | 0.88 | MCHR1 (0.46) | MCHR1PDCD1LG2CD274DRD2DRD4 | |
| SCHEMBL18864046 | 0.88 | MCHR1 (0.46) | MCHR1PDCD1LG2CD274DRD2DRD4 | |
| SCHEMBL18890847 | 0.83 | MCHR1 (0.42) | MCHR1CA1CA2DDR1KDM4D | |
| SCHEMBL18864135 | 0.83 | DRD4 (0.43) | MCHR1CD274DRD2DRD4DRD3 | |
| SCHEMBL18864155 | 0.83 | DRD4 (0.43) | MCHR1CD274DRD2DRD4DRD3 | |
| SCHEMBL18864137 | 0.83 | DRD4 (0.43) | MCHR1CD274DRD2DRD4DRD3 | |
| SCHEMBL17076312 | 0.79 | MAPK1 (0.53) | — | |
| SCHEMBL17076311 | 0.79 | MAPK1 (0.53) | — | |
| SCHEMBL14734906 | 0.77 | CHRM2 (0.41) | PDE4BPDE11APDE10ACD274CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170145005-A1 | KINASE INHIBITOR | THE UNIVERSITY OF TOKYO (JP) | 2017-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170145005-A1 | KINASE INHIBITOR | PIM3, PIM1, PIM2 | MCHR1 3515/4885CA1 4164/4885CA2 2402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.