Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18892033 | 0.88 | CYP3A4 (0.54) | CYP3A4 | |
| SCHEMBL18892390 | 0.87 | CYP3A4 (0.71) | CYP3A4 | |
| SCHEMBL1699573 | 0.87 | CYP3A4 (0.71) | CYP3A4 | |
| SCHEMBL1699612 | 0.87 | CYP3A4 (0.71) | CYP3A4 | |
| SCHEMBL15165231 | 0.87 | CYP3A4 (0.64) | CYP3A4 | |
| SCHEMBL15165237 | 0.87 | CYP3A4 (0.64) | CYP3A4 | |
| SCHEMBL10271709 | 0.84 | CYP3A4 (0.71) | CYP3A4 | |
| SCHEMBL18892329 | 0.84 | CYP3A4 (0.71) | CYP3A4 | |
| SCHEMBL15165239 | 0.83 | CYP3A4 (0.64) | CYP3A4 | |
| SCHEMBL26076728 | 0.82 | CYP3A4 (0.77) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588450-B1 | NAPHT-2-YLACETIC ACID DERIVATIVES TO TREAT AIDS | GILEAD SCIENCES INC (US) | 2017-05-24 | — | — | EP | disclosed |