Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18895982 | 0.81 | — | — | |
| SCHEMBL12121700 | 0.78 | CYP19A1 (0.31) | CYP19A1 | |
| SCHEMBL14420192 | 0.67 | CCR1 (0.32) | CCR1 | |
| SCHEMBL13824505 | 0.66 | CCR1 (0.32) | CCR1 | |
| SCHEMBL18633827 | 0.64 | CCR1 (0.39) | CCR1 | |
| SCHEMBL16312668 | 0.63 | CCR1 (0.39) | CCR1 | |
| SCHEMBL14579593 | 0.63 | TBXA2R (0.31) | CCR1 | |
| SCHEMBL15478381 | 0.61 | CCR1 (0.38) | CCR1 | |
| SCHEMBL436922 | 0.58 | CCR1 (0.59) | CCR1 | |
| SCHEMBL14579805 | 0.58 | CCR1 (0.59) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663537-B2 | Chemokine receptor antagonists and methods of use | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-05-30 | — | — | US | disclosed |