Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | UBE2M | P61081 | 1/20 | 0.31 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL654316 | 0.83 | CCR1 (0.58) | CCR1MCHR1KCNH2OPRM1CHRM2 | |
| SCHEMBL15478322 | 0.83 | CCR1 (0.58) | CCR1MCHR1KCNH2OPRM1CHRM2 | |
| SCHEMBL654317 | 0.83 | CCR1 (0.58) | CCR1MCHR1KCNH2OPRM1CHRM2 | |
| SCHEMBL656212 | 0.78 | CCR1 (0.57) | CCR1MCHR1OPRM1CHRM2CCR5 | |
| SCHEMBL656211 | 0.78 | CCR1 (0.57) | CCR1MCHR1OPRM1CHRM2CCR5 | |
| SCHEMBL18895971 | 0.77 | CCR1 (0.60) | CCR1MCHR1OPRM1CHRM2CCR5 | |
| SCHEMBL655288 | 0.77 | CCR1 (0.60) | CCR1MCHR1OPRM1CHRM2CCR5 | |
| SCHEMBL655287 | 0.77 | CCR1 (0.60) | CCR1MCHR1OPRM1CHRM2CCR5 | |
| SCHEMBL18633833 | 0.77 | CCR1 (0.42) | CCR1 | |
| SCHEMBL656375 | 0.76 | CCR1 (0.57) | CCR1MCHR1CHRM2CCR5UBE2M |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663537-B2 | Chemokine receptor antagonists and methods of use | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-05-30 | — | — | US | disclosed |