Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18648975 | 0.87 | GLA (0.54) | GLAFOLH1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20170038 | 0.87 | GLA (0.54) | GLAFOLH1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22296455 | 0.82 | GLA (0.53) | GLAFOLH1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2660512 | 0.81 | GLA (0.58) | GLAFOLH1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19407082 | 0.80 | CYP2A6 (0.53) | SLC6A2SLC6A4SLC6A3MAOBCYP19A1 | |
| SCHEMBL5262783 | 0.80 | GLA (0.57) | GLAFOLH1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4496028 | 0.80 | GLA (0.57) | GLAFOLH1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21316490 | 0.78 | GLA (0.55) | GLAFOLH1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28046794 | 0.78 | GLA (0.55) | GLAFOLH1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19954266 | 0.77 | GLA (0.48) | GLAFOLH1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9662335-B2 | Heteroaryl substituted pyrrolo[2,3-B] pyridines and pyrrolo[2,3-B] pyrimidines as janus kinase inhibitors | INCYTE HOLDINGS CORPORATION (US) | 2017-05-30 | — | — | US | disclosed |