Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.76 |
| ▸ | GSTP1 | P09211 | 15/20 | 0.71 |
| ▸ | GSTM2 | P28161 | 15/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | NSD2 | O96028 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL297920 | 0.86 | IDO1 (1.00) | IDO1GSTP1GSTM2CASP6 | |
| SCHEMBL6833698 | 0.85 | IDO1 (0.78) | IDO1GSTP1GSTM2KDM4EMEN1 | |
| SCHEMBL18895761 | 0.84 | IDO1 (0.76) | IDO1GSTP1GSTM2KDM4EMEN1 | |
| SCHEMBL297980 | 0.84 | IDO1 (1.00) | IDO1GSTP1GSTM2KDM4EMEN1 | |
| SCHEMBL6049433 | 0.84 | IDO1 (0.76) | IDO1GSTP1GSTM2 | |
| SCHEMBL18895758 | 0.84 | IDO1 (0.76) | IDO1GSTP1GSTM2KDM4EMEN1 | |
| SCHEMBL6831327 | 0.84 | IDO1 (0.76) | IDO1GSTP1GSTM2KDM4EMEN1 | |
| SCHEMBL6831349 | 0.84 | IDO1 (0.76) | IDO1GSTP1GSTM2KDM4EMEN1 | |
| SCHEMBL6836307 | 0.83 | GSTP1 (1.00) | IDO1GSTP1GSTM2KDM4EMEN1 | |
| SCHEMBL18878879 | 0.83 | IDO1 (0.74) | IDO1GSTP1GSTM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9664696-B1 | Compounds for determining the presence of hydrogen sulfide and methods of use | UNIVERSITY OF OREGON (US) | 2017-05-30 | — | — | US | disclosed |