Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 18/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17698656 | 0.76 | BRD4 (0.46) | BRD4ERN1NR3C1PGR | |
| SCHEMBL17698773 | 0.74 | NR3C2 (0.47) | BRD4ERN1NR3C1PGR | |
| SCHEMBL17773288 | 0.66 | BRD4 (0.47) | BRD4 | |
| SCHEMBL16132522 | 0.65 | BRD4 (0.54) | BRD4ERN1 | |
| SCHEMBL18635774 | 0.63 | BRD4 (0.44) | BRD4ERN1 | |
| SCHEMBL17698710 | 0.63 | BRD4 (0.47) | BRD4ERN1 | |
| SCHEMBL16225464 | 0.63 | BRD4 (0.51) | BRD4ERN1 | |
| SCHEMBL18635203 | 0.63 | BRD4 (0.51) | BRD4ERN1 | |
| SCHEMBL24224631 | 0.62 | BRD4 (0.51) | BRD4 | |
| SCHEMBL16225958 | 0.62 | BRD4 (1.00) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9662311-B2 | Substituted bicyclic compounds as bromodomain inhibitors | ZENITH EPIGENETICS LTD. (CA) | 2017-05-30 | — | — | US | disclosed |