Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PDE6A | P16499 | 1/20 | 0.34 |
| ▸ | PDE6B | P35913 | 1/20 | 0.34 |
| ▸ | PDE1A | P54750 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.30 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
| ▸ | CCND2 | P30279 | 1/20 | 0.30 |
| ▸ | CCND3 | P30281 | 1/20 | 0.30 |
| ▸ | CASR | P41180 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17807776 | 0.78 | CASR (0.36) | MAOBCASR | |
| SCHEMBL23507965 | 0.78 | BTK (0.43) | MAOBBTKCDK4CCND1CCND2 | |
| SCHEMBL19200854 | 0.74 | MAOB (0.38) | MAOBPDE6APDE6BPDE1APDE1B | |
| SCHEMBL22419359 | 0.72 | PPARG (0.36) | MAOBPDE6APDE6BPDE1APDE1B | |
| SCHEMBL20251119 | 0.70 | CDK4 (0.38) | CDK4CCND1CCND2CCND3 | |
| SCHEMBL15340919 | 0.67 | MAPK1 (0.32) | — | |
| SCHEMBL16663602 | 0.66 | KDM4E (0.34) | PDE1APDE1BPDE1CCDK4 | |
| SCHEMBL25092979 | 0.66 | MAOB (0.47) | MAOBPDE6APDE6BPDE1APDE1B | |
| SCHEMBL19759412 | 0.62 | PIK3CB (0.39) | — | |
| SCHEMBL21024080 | 0.62 | HSD17B10 (0.59) | PDE6APDE6BPDE1APDE1BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663520-B2 | Bicyclic bromodomain inhibitors | ZENITH EPIGENETICS LTD. (CA) | 2017-05-30 | — | — | US | disclosed |