Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 5/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.32 |
| ▸ | IL6 | P05231 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CCND2 | P30279 | 1/20 | 0.31 |
| ▸ | CCND3 | P30281 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | PDE6C | P51160 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL976625 | 0.87 | CYP1A2 (0.66) | MTORCYP1A2FYNMAP3K11PDE4D | |
| SCHEMBL975430 | 0.83 | FYN (0.54) | MTORCYP1A2FYN | |
| SCHEMBL975431 | 0.83 | FYN (0.54) | MTORCYP1A2FYN | |
| SCHEMBL19200211 | 0.80 | MTOR (0.53) | MTORCYP1A2FYNCDK1POLB | |
| SCHEMBL17807738 | 0.79 | MTOR (0.58) | MTORCYP1A2FYNPOLBMAPK8 | |
| SCHEMBL481934 | 0.79 | MTOR (0.58) | MTORCYP1A2FYNCDK1POLB | |
| SCHEMBL24995677 | 0.77 | MTOR (0.55) | MTORCYP1A2FYNPOLBMAPK8 | |
| SCHEMBL975519 | 0.77 | MTOR (0.55) | MTORCYP1A2FYNPOLBMAPK8 | |
| SCHEMBL977817 | 0.75 | CYP1A2 (0.55) | MTORCYP1A2PDE4D | |
| SCHEMBL19200146 | 0.75 | POLB (0.44) | MTORCDK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663520-B2 | Bicyclic bromodomain inhibitors | ZENITH EPIGENETICS LTD. (CA) | 2017-05-30 | — | — | US | disclosed |