Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132979 | 0.88 | PDK2 (0.50) | PDK2HPGDNPC1RAB9AMAPT | |
| SCHEMBL21845661 | 0.86 | PDK2 (0.52) | PDK2RXRAHPGDPTGS1PTGS2 | |
| SCHEMBL134303 | 0.82 | PDK2 (0.49) | PDK2HPGDNPC1RAB9ATDP1 | |
| SCHEMBL12856537 | 0.82 | PDK2 (0.49) | PDK2HPGDNPC1RAB9ATDP1 | |
| SCHEMBL22175308 | 0.79 | PDK2 (0.42) | PDK2HPGDNPC1RAB9AMAPT | |
| SCHEMBL13781052 | 0.78 | PDK2 (0.49) | PDK2HPGDNPC1RAB9AMAPT | |
| SCHEMBL12604139 | 0.78 | PDK2 (0.50) | PDK2HPGDNPC1RAB9APTGS1 | |
| SCHEMBL18900386 | 0.78 | PDK2 (0.39) | PDK2 | |
| SCHEMBL13781081 | 0.77 | PDK2 (0.44) | PDK2RXRAHPGDNPC1RAB9A | |
| SCHEMBL30534206 | 0.76 | PDK2 (0.46) | PDK2HPGDNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791275-B1 | ORGANIC SENSITIZERS FOR UP-CONVERSION | MERCK PATENT GMBH (DE) | 2017-05-31 | — | — | EP | disclosed |