Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.58 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536680 | 0.88 | S1PR1 (0.64) | S1PR1S1PR5S1PR3 | |
| SCHEMBL18901483 | 0.85 | S1PR1 (0.64) | S1PR1S1PR3 | |
| SCHEMBL18901338 | 0.83 | S1PR1 (0.50) | S1PR1S1PR3 | |
| SCHEMBL18901454 | 0.82 | S1PR1 (0.55) | S1PR1S1PR5S1PR3 | |
| SCHEMBL558227 | 0.81 | S1PR1 (0.68) | S1PR1S1PR5S1PR3 | |
| SCHEMBL536610 | 0.81 | S1PR1 (0.61) | S1PR1S1PR5S1PR3 | |
| SCHEMBL18901357 | 0.80 | S1PR1 (0.59) | S1PR1S1PR3 | |
| SCHEMBL410702 | 0.79 | S1PR1 (0.59) | S1PR1S1PR5S1PR3 | |
| SCHEMBL10170521 | 0.79 | NR1H4 (0.54) | S1PR1S1PR5S1PR3 | |
| SCHEMBL558070 | 0.79 | S1PR1 (0.67) | S1PR1S1PR5S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414342-B1 | OXADIAZOLE DERIVATIVES | MERCK SERONO SA (CH) | 2017-05-31 | — | — | EP | disclosed |