Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13147239 | 0.92 | S1PR1 (0.52) | S1PR1S1PR3 | |
| SCHEMBL558902 | 0.91 | S1PR1 (0.58) | S1PR1S1PR3 | |
| SCHEMBL18901338 | 0.91 | S1PR1 (0.50) | S1PR1S1PR3NPC1 | |
| SCHEMBL408484 | 0.86 | S1PR1 (0.50) | S1PR1S1PR3 | |
| SCHEMBL558155 | 0.83 | S1PR1 (0.61) | S1PR1S1PR3 | |
| SCHEMBL18901357 | 0.81 | S1PR1 (0.59) | S1PR1S1PR3 | |
| SCHEMBL558227 | 0.81 | S1PR1 (0.68) | S1PR1S1PR3 | |
| SCHEMBL557834 | 0.80 | S1PR1 (0.73) | S1PR1S1PR3 | |
| SCHEMBL18901333 | 0.79 | S1PR1 (0.53) | S1PR1S1PR3NPC1 | |
| SCHEMBL16705110 | 0.79 | S1PR1 (0.69) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414342-B1 | OXADIAZOLE DERIVATIVES | MERCK SERONO SA (CH) | 2017-05-31 | — | — | EP | disclosed |