SCHEMBL18901595

SCHEMBL18901595

NCC(CCc1ccc(F)cc1)Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MKNK1 Q9BUB5 20/20 0.66
MKNK2 Q9HBH9 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18901371 0.93 MKNK1 (0.70) MKNK1MKNK2
SCHEMBL14764275 0.91 MKNK1 (0.68) MKNK1MKNK2
SCHEMBL14764083 0.87 MKNK1 (0.81) MKNK1MKNK2
SCHEMBL18901370 0.87 MKNK1 (0.67) MKNK1MKNK2
SCHEMBL14764069 0.84 MKNK1 (0.70) MKNK1MKNK2
SCHEMBL14764028 0.84 MKNK1 (0.73) MKNK1MKNK2
SCHEMBL14763963 0.83 MKNK1 (0.69) MKNK1MKNK2
SCHEMBL14764314 0.83 MKNK1 (0.80) MKNK1MKNK2
SCHEMBL18901400 0.83 MKNK1 (0.74) MKNK1MKNK2
SCHEMBL14771361 0.83 MKNK1 (0.66) MKNK1MKNK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2758401-B1 AMINO-SUBSTITUTED IMIDAZOPYRIDAZINES BAYER IP GMBH (DE) 2017-05-31 EP disclosed