Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17467207 | 0.91 | EGFR (1.00) | EGFR | |
| SCHEMBL17467077 | 0.81 | EGFR (1.00) | EGFR | |
| SCHEMBL19239594 | 0.81 | EGFR (0.82) | EGFR | |
| SCHEMBL17467392 | 0.79 | EGFR (0.79) | EGFR | |
| SCHEMBL17467229 | 0.79 | EGFR (0.79) | EGFR | |
| SCHEMBL17467210 | 0.79 | EGFR (1.00) | EGFR | |
| SCHEMBL17467050 | 0.77 | EGFR (1.00) | EGFR | |
| SCHEMBL17467209 | 0.77 | EGFR (1.00) | EGFR | |
| SCHEMBL17467220 | 0.77 | EGFR (0.76) | EGFR | |
| SCHEMBL21517139 | 0.77 | EGFR (0.84) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3173412-A1 | 2,4-DISUBSTITUTED 7H-PYRROLO[2,3-D]PYRIMIDINE DERIVATIVE, PREPARATION METHOD AND MEDICINAL USE THEREOF | Shanghai Haiyan Pharmaceutical Technology Co., Ltd. (CN) | 2017-05-31 | — | — | EP | disclosed |