Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.70 |
| ▸ | BRD2 | P25440 | 5/20 | 0.63 |
| ▸ | BRD3 | Q15059 | 5/20 | 0.63 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12098683 | 0.86 | BRD4 (0.69) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL18904315 | 0.85 | BRD4 (0.70) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL13731723 | 0.85 | BRD4 (0.74) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL12099187 | 0.84 | BRD4 (0.69) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL13731941 | 0.83 | BRD4 (0.74) | BRD4CYP3A4CYP2C9 | |
| SCHEMBL12098991 | 0.83 | BRD4 (0.81) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL12098996 | 0.83 | BRD4 (0.67) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL15974912 | 0.83 | BRD4 (0.67) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL15984947 | 0.83 | BRD4 (0.64) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL15464909 | 0.82 | BRD4 (1.00) | BRD4CYP3A4CYP2C9BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699573-B1 | 7-(3,5-DIMETHYL-4-ISOXAZOLYL)-8-(METHYLOXY)-1H-IMIDAZO[4,5-C]QUINOLINE DERIVATIVES | GLAXOSMITHKLINE LLC (US) | 2017-05-31 | — | — | EP | disclosed |