SCHEMBL18904500

SCHEMBL18904500

C(=C/c1ccc2ccc3cccnc3c2n1)\c1ccc(-c2ccc3c4ccccc4c4ccccc4c3c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CD74 P04233 1/20 0.42
▸ MIF P14174 1/20 0.42
▸ SMN1; SMN2 Q16637 6/20 0.40
▸ LMNA P02545 6/20 0.40
▸ KDM4E B2RXH2 5/20 0.40
▸ MAPT P10636 4/20 0.40
▸ HTT P42858 3/20 0.40
▸ HSP90AA1 P07900 2/20 0.40
▸ NFKB1 P19838 2/20 0.40
▸ CCR1 P32246 2/20 0.40
▸ CCR5 P51681 2/20 0.40
▸ CCR8 P51685 2/20 0.40
▸ TP53 P04637 2/20 0.40
▸ ALOX15 P16050 2/20 0.40
▸ GMNN O75496 1/20 0.40
▸ MMP2 P08253 1/20 0.40
▸ CYP3A4 P08684 1/20 0.40
▸ CYP2D6 P10635 1/20 0.40
▸ MMP9 P14780 1/20 0.40
▸ TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18904499 0.90 CCR1 (0.44) CD74MIFSMN1; SMN2LMNAKDM4E
SCHEMBL18904464 0.88 MEN1 (0.36) CD74MIFSMN1; SMN2LMNAKDM4E
SCHEMBL31300953 0.81 KDM4E (0.57) CD74MIFSMN1; SMN2LMNAKDM4E
SCHEMBL13808799 0.81 MEN1 (0.39) CD74MIFSMN1; SMN2LMNAKDM4E
SCHEMBL18902518 0.79 CCR1 (0.47) SMN1; SMN2LMNAKDM4EMAPTHTT
SCHEMBL30960849 0.79 CCR1 (0.47) SMN1; SMN2LMNAKDM4EMAPTHTT
SCHEMBL17899299 0.79 CCR1 (0.47) SMN1; SMN2LMNAKDM4EMAPTHTT
SCHEMBL18904452 0.79 CCR1 (0.47) SMN1; SMN2LMNAKDM4EMAPTHTT
SCHEMBL18905569 0.78 MEN1 (0.32) HSP90AA1CCR1CCR8NPC1RAB9A
SCHEMBL17899331 0.78 CCR1 (0.67) CD74MIFSMN1; SMN2LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10177317-B2 Organic light emitting display device LG DISPLAY CO., LTD. (KR) 2019-01-08 — — US disclosed
US-20170155055-A1 ORGANIC LIGHT EMITTING DISPLAY DEVICE LG DISPLAY CO., LTD. (KR) 2017-06-01 — — US disclosed
US-20170155055-A1 ORGANIC LIGHT EMITTING DISPLAY DEVICE LG DISPLAY CO., LTD. (KR) 2017-06-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10177317-B2 Organic light emitting display device OCIAD2, L1CAM, OCIAD1 CD74 1074/4885MIF 2030/4885SMN1; SMN2 3707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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