Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15244016 | 0.87 | KDM4E (0.57) | KDM4EHTTALDH1A1MAPTNSD2 | |
| SCHEMBL18168045 | 0.81 | HTT (0.39) | KDM4EHTTALDH1A1MAPTNSD2 | |
| SCHEMBL31351030 | 0.80 | IRAK4 (0.45) | KDM4EALDH1A1MAPTNSD2IRAK4 | |
| SCHEMBL18023207 | 0.80 | HDAC6 (0.42) | KDM4EMAPTHDAC6IRAK4POLB | |
| SCHEMBL16569404 | 0.80 | HDAC8 (0.40) | HTTALDH1A1MAPTHDAC6IRAK4 | |
| SCHEMBL29141447 | 0.80 | IRAK4 (0.40) | MAPTHDAC6IRAK4HDAC2HDAC3 | |
| SCHEMBL17981699 | 0.80 | KMT2A (0.44) | KDM4EALDH1A1MAPTHDAC6IRAK4 | |
| SCHEMBL26442592 | 0.80 | HDAC6 (0.40) | KDM4EALDH1A1MAPTHDAC6IRAK4 | |
| SCHEMBL5860842 | 0.80 | KDM4E (0.41) | KDM4EHTTALDH1A1MAPTNSD2 | |
| SCHEMBL188317 | 0.79 | KDM4E (0.43) | KDM4EHTTALDH1A1MAPTNSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101948433-B | Method for separating and purifying substituted indazole isomer | UNIV ZHENGZHOU | 2012-05-09 | — | — | CN | claimed |
| CN-101948433-A | Method for separating and purifying substituted indazole isomers | UNIV ZHENGZHOU | 2011-01-19 | — | — | CN | claimed |
| US-20240043439-A1 | COMPOUNDS AS C5AR INHIBITORS | KIRA PHARMACEUTICALS (SUZHOU) LTD. (CN) | 2024-02-08 | — | — | US | disclosed |
| CN-113292539-B | Substituted oxopyridine derivatives | 拜耳制药股份公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-116322683-A | Compounds as C5AR inhibitors | 科越医药(苏州)有限公司 | 2023-06-23 | — | — | CN | disclosed |
| EP-4192816-A1 | COMPOUNDS AS C5AR INHIBITORS | Kira Pharmaceuticals (Suzhou) Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022028586-A1 | COMPOUNDS AS C5AR INHIBITORS | KIRA PHARMACEUTICALS (SUZHOU) LTD. (CN) | 2022-02-10 | — | — | WO | disclosed |
| CN-113292539-A | Substituted oxopyridine derivatives | 拜耳制药股份公司 | 2021-08-24 | — | — | CN | disclosed |
| CN-108026072-B | Substituted oxopyridine derivatives | 拜耳制药股份公司 | 2021-08-17 | — | — | CN | disclosed |
| US-20170152232-A1 | NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND | ASTELLAS PHARMA INC. (JP) | 2017-06-01 | — | — | US | disclosed |
| US-20170152232-A1 | NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND | ASTELLAS PHARMA INC. (JP) | 2017-06-01 | — | — | US | disclosed |
| CN-101948433-B | Method for separating and purifying substituted indazole isomer | UNIV ZHENGZHOU | 2012-05-09 | — | — | CN | disclosed |
| CN-101948433-A | Method for separating and purifying substituted indazole isomers | UNIV ZHENGZHOU | 2011-01-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152232-A1 | NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND | FGFR3, FGFR1, FGFR2 | KDM4E 600/4885HTT 181/4885ALDH1A1 1432/4885 |
| US-20240043439-A1 | COMPOUNDS AS C5AR INHIBITORS | C5AR1, C5AR2, C3AR1 | KDM4E 4189/4885HTT 4089/4885ALDH1A1 3678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.