SCHEMBL18906407

SCHEMBL18906407

COC(=O)N1c2ccc(C)cc2Sc2cc(C)ccc21

nearest known ligand 0.63

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
BCHE P06276 14/20 0.63
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 2/20 0.44
MAPT P10636 2/20 0.44
KMT2A Q03164 2/20 0.44
HPGD P15428 2/20 0.44
ALOX12 P18054 1/20 0.44
P2RX4 Q99571 2/20 0.44
ALOX15 P16050 1/20 0.42
MAPK1 P28482 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15237151 0.87 BCHE (0.63) BCHEKDM4EMEN1MAPTKMT2A
SCHEMBL17356860 0.85 BCHE (0.67) BCHEMEN1MAPTKMT2AHPGD
SCHEMBL14492352 0.80 MAPK1 (0.62) BCHEMEN1MAPTKMT2AP2RX4
SCHEMBL8739119 0.77 BCHE (1.00) BCHEKDM4EMAPTP2RX4
SCHEMBL18904511 0.75 BCHE (0.47) BCHEMEN1MAPTKMT2AHPGD
SCHEMBL25840356 0.74 BCHE (0.63) BCHEMEN1MAPTKMT2AHPGD
SCHEMBL17356858 0.74 MAPT (0.51) KDM4EMEN1MAPTKMT2AHPGD
SCHEMBL17356855 0.73 BCHE (0.66) BCHEMEN1KMT2AHPGDP2RX4
SCHEMBL17356853 0.73 BCHE (0.41) BCHEMEN1MAPTKMT2AHPGD
SCHEMBL17356865 0.73 TDP1 (0.51) KDM4EMEN1MAPTKMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170153547-A1 COATING COMPOSITIONS FOR USE WITH AN OVERCOATED PHOTORESIST DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-06-01 US disclosed