Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | CETP | P11597 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.54 |
| ▸ | DGKA | P23743 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29536611 | 0.88 | PPARG (0.58) | EPHX2ALDH1A1TP53CETPTHRB | |
| SCHEMBL8983126 | 0.87 | EPHX2 (0.73) | EPHX2ALDH1A1TP53MEN1KMT2A | |
| SCHEMBL20683604 | 0.87 | EPHX2 (0.73) | EPHX2ALDH1A1TP53MEN1KMT2A | |
| SCHEMBL7934641 | 0.87 | EPHX2 (0.73) | EPHX2ALDH1A1TP53MEN1KMT2A | |
| SCHEMBL23918136 | 0.87 | EPHX2 (0.73) | EPHX2ALDH1A1TP53MEN1KMT2A | |
| Methyl Oleate SCHEMBL25202566 | 0.87 | EPHX2 (0.73) | EPHX2ALDH1A1TP53MEN1KMT2A | |
| Methyl Oleate SCHEMBL37372 | 0.87 | EPHX2 (0.73) | EPHX2ALDH1A1TP53MEN1KMT2A | |
| SCHEMBL24751538 | 0.87 | EPHX2 (0.73) | EPHX2ALDH1A1TP53MEN1KMT2A | |
| SCHEMBL20991368 | 0.87 | EPHX2 (0.73) | EPHX2ALDH1A1TP53MEN1KMT2A | |
| SCHEMBL16322908 | 0.87 | EPHX2 (0.73) | EPHX2ALDH1A1TP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017091279-A1 | SITE-SPECIFIC ISOTOPIC LABELING OF 1, 4-DIENE SYSTEMS | RETROTOPE, INC. (US) | 2017-06-01 | — | — | WO | disclosed |