SCHEMBL18908545

SCHEMBL18908545

CC1=Cc2c(F)c(F)c(F)c(F)c2C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL689864 0.63
SCHEMBL18033929 0.62
SCHEMBL15001025 0.60
SCHEMBL16393608 0.59
SCHEMBL5953856 0.58 CYP3A4 (0.30)
SCHEMBL17581052 0.57
SCHEMBL15460010 0.55
SCHEMBL5705533 0.53
SCHEMBL7002117 0.53
SCHEMBL11891725 0.51

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11655264-B2 Metallocene compounds, and preparation and use thereof for synthesis of poly-alpha-olefins as lubricating base oil APALENE TECHNOLOGY CO., LTD. (HANGZHOU) (CN) 2023-05-23 US disclosed
US-11655264-B2 Metallocene compounds, and preparation and use thereof for synthesis of poly-alpha-olefins as lubricating base oil APALENE TECHNOLOGY CO., LTD. (HANGZHOU) (CN) 2023-05-23 US disclosed
WO-2017088279-A1 METALLOCENE POLYALPHAOLEFIN CATALYST FOR SYNTHETIC LUBRICANT BASE STOCKS, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 亚培烯科技(嘉兴)有限公司 2017-06-01 WO disclosed