⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22928683 | 0.76 | — | — | |
| SCHEMBL18878041 | 0.73 | — | — | |
| SCHEMBL7142728 | 0.67 | — | — | |
| SCHEMBL18780014 | 0.67 | — | — | |
| SCHEMBL201118 | 0.64 | — | — | |
| SCHEMBL2472853 | 0.64 | — | — | |
| SCHEMBL1320186 | 0.62 | — | — | |
| SCHEMBL2538211 | 0.62 | — | — | |
| SCHEMBL24009620 | 0.62 | — | — | |
| SCHEMBL11354925 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017091585-A1 | EIF4-A-INHIBITING COMPOUNDS AND METHODS RELATED THERETO | EFFECTOR THERAPEUTICS, INC. (US) | 2017-06-01 | — | — | WO | disclosed |