Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18202242 | 0.98 | EGFR (0.51) | EGFRKCNH2 | |
| SCHEMBL18911707 | 0.93 | EGFR (0.51) | EGFRKCNH2 | |
| SCHEMBL18202325 | 0.91 | EGFR (0.60) | EGFRKCNH2 | |
| SCHEMBL18202166 | 0.89 | EGFR (0.60) | EGFRKCNH2 | |
| SCHEMBL19930427 | 0.89 | EGFR (0.64) | EGFRKCNH2 | |
| SCHEMBL19930431 | 0.89 | EGFR (0.49) | EGFR | |
| SCHEMBL19930430 | 0.88 | EGFR (0.54) | EGFRKCNH2 | |
| SCHEMBL20080093 | 0.88 | EGFR (0.50) | EGFR | |
| SCHEMBL18202330 | 0.86 | EGFR (0.55) | EGFRKCNH2 | |
| SCHEMBL18911733 | 0.86 | EGFR (0.71) | EGFRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312179-B1 | FUSED-RING OR TRICYCLIC ARYL PYRIMIDINE COMPOUND USED AS KINASE INHIBITOR | NANJING SANHOME PHARMACEUTICAL CO LTD (CN) | 2019-07-10 | — | — | EP | disclosed |
| WO-2017088746-A1 | NEW EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITOR AND APPLICATION THEREOF | 南京圣和药业股份有限公司 | 2017-06-01 | — | — | WO | disclosed |