Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4166313 | 0.85 | SMN1; SMN2 (0.41) | TP53L3MBTL1MAPTSMN1; SMN2POLB | |
| SCHEMBL1169069 | 0.85 | KDM4C (0.47) | TP53KDM4CKDM6BKDM4DL3MBTL1 | |
| SCHEMBL4715967 | 0.80 | BRD4 (0.44) | L3MBTL1MAPTSMN1; SMN2POLBKDM4E | |
| SCHEMBL4153764 | 0.80 | MAPT (0.41) | L3MBTL1MAPTSMN1; SMN2POLBTDP1 | |
| SCHEMBL4161486 | 0.78 | BRD4 (0.46) | TP53L3MBTL1MAPTSMN1; SMN2POLB | |
| SCHEMBL12660312 | 0.78 | BRD4 (0.68) | TP53L3MBTL1MAPTSMN1; SMN2POLB | |
| SCHEMBL4716111 | 0.78 | NTRK1 (0.45) | L3MBTL1MAPTSMN1; SMN2POLBTDP1 | |
| SCHEMBL1887669 | 0.78 | HTT (0.57) | TP53L3MBTL1MAPTSMN1; SMN2POLB | |
| SCHEMBL15286826 | 0.77 | KDM4C (0.70) | TP53KDM4CKDM6BKDM4DL3MBTL1 | |
| SCHEMBL15295150 | 0.77 | TP53 (0.54) | TP53KDM4CKDM6BMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7947679-B2 | Fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-05-24 | — | — | US | disclosed |
| US-7947679-B2 | Fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-05-24 | — | — | US | disclosed |
| US-7947679-B2 | Fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-05-24 | — | — | US | disclosed |
| EP-1585746-B1 | NAPHTHYRIDINE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA LTD (GB) | 2007-01-31 | — | — | EP | disclosed |
| US-20060069089-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. | 2006-03-30 | — | — | US | disclosed |
| EP-1585746-A2 | NAPHTHYRIDINE DERIVATIVES AND THEIR USE AS FUNGICIDES | Syngenta Limited (GB) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004056824-A2 | NAPHTHYRIDINE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069089-A1 | Fungicides | CBR3, TACR3, HCRTR1 | TP53 4540/4885KDM4C 477/4885KDM6B 1361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.