Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10284199 | 1.00 | EPHX1 (0.51) | EPHX1EPHX2CHRNB4CHRNA3SIGMAR1 | |
| SCHEMBL2759379 | 0.96 | EPHX1 (0.56) | EPHX1EPHX2CHRNB4CHRNA3SIGMAR1 | |
| SCHEMBL19696814 | 0.94 | EPHX1 (0.59) | EPHX1EPHX2CHRNB4CHRNA3SIGMAR1 | |
| SCHEMBL10308298 | 0.94 | EPHX1 (0.59) | EPHX1EPHX2CHRNB4CHRNA3SIGMAR1 | |
| SCHEMBL12975489 | 0.92 | SMYD3 (0.50) | EPHX1EPHX2CHRNB4CHRNA3SIGMAR1 | |
| SCHEMBL10283928 | 0.92 | SMYD3 (0.50) | EPHX1EPHX2CHRNB4CHRNA3SIGMAR1 | |
| SCHEMBL18880091 | 0.86 | CHRNB4 (0.46) | EPHX1EPHX2CHRNB4CHRNA3SIGMAR1 | |
| SCHEMBL24996526 | 0.83 | SMYD3 (0.64) | EPHX1EPHX2CHRNB4CHRNA3SMYD3 | |
| SCHEMBL21730427 | 0.83 | EPHX1 (0.52) | EPHX1EPHX2CHRNB4CHRNA3SIGMAR1 | |
| SCHEMBL10098777 | 0.82 | CHRNB4 (0.54) | EPHX2CHRNB4CHRNA3SIGMAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017091600-A1 | PYRAZOLE ACC INHIBITORS AND USES THEREOF | GILEAD APOLLO, LLC (US) | 2017-06-01 | — | — | WO | disclosed |