Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 8/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6407728 | 1.00 | PDE5A (0.83) | PDE5A | |
| SCHEMBL6407365 | 0.92 | PDE5A (0.80) | PDE5A | |
| SCHEMBL6407149 | 0.91 | PDE5A (1.00) | PDE5A | |
| SCHEMBL6411593 | 0.88 | PDE5A (0.82) | PDE5A | |
| SCHEMBL6407720 | 0.86 | PDE5A (0.76) | PDE5A | |
| SCHEMBL5530466 | 0.86 | PDE5A (0.84) | PDE5A | |
| SCHEMBL1887265 | 0.86 | PDE5A (0.84) | PDE5A | |
| SCHEMBL6788029 | 0.85 | PDE5A (0.80) | PDE5A | |
| SCHEMBL6405899 | 0.85 | PDE5A (0.74) | PDE5A | |
| SCHEMBL6290558 | 0.82 | PDE5A (1.00) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3875078-A1 | COMPOUNDS FOR THE TREATMENT OF COVID-19 | Dompe' Farmaceutici S.P.A. (IT) | 2021-09-08 | — | — | EP | claimed |
| EP-3875078-A1 | COMPOUNDS FOR THE TREATMENT OF COVID-19 | Dompe' Farmaceutici S.P.A. (IT) | 2021-09-08 | — | — | EP | disclosed |
| US-20150086504-A1 | POLYMERIC MICROEMULSIONS | JANSSEN PHARMACEUTICA NV (BE) | 2015-03-26 | — | — | US | disclosed |
| US-20110112115-A1 | POLYMERIC MICROEMULSIONS | ARIEN ALBERTINA MARIA EDUARDA | 2011-05-12 | — | — | US | disclosed |
| EP-1504047-B1 | POLYMERIC MICROEMULSIONS | JANSSEN PHARMACEUTICA NV (BE) | 2007-12-12 | — | — | EP | disclosed |
| US-20060034797-A1 | Polymeric micromulsions | ETHICON INC. | 2006-02-16 | — | — | US | disclosed |
| EP-1504047-A1 | POLYMERIC MICROEMULSIONS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-09 | — | — | EP | disclosed |
| WO-2003093344-A1 | POLYMERIC MICROEMULSIONS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-11-13 | — | — | WO | disclosed |