⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1655666 | 0.69 | — | — | |
| SCHEMBL9131744 | 0.69 | — | — | |
| SCHEMBL9342 | 0.64 | — | — | |
| SCHEMBL385771 | 0.64 | — | — | |
| SCHEMBL645217 | 0.64 | — | — | |
| SCHEMBL7105534 | 0.64 | TSHR (0.31) | — | |
| SCHEMBL1760694 | 0.64 | — | — | |
| SCHEMBL686751 | 0.64 | — | — | |
| SCHEMBL275800 | 0.64 | — | — | |
| SCHEMBL6989643 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1922315-B1 | PREPARATION OF AN ATORVASTATIN INTERMEDIATE | PFIZER SCIENCE & TECH LTD (IE) | 2009-05-27 | — | — | EP | claimed |
| US-9079877-B2 | Process for preparing chiral compounds | PFIZER INC. (US) | 2015-07-14 | — | — | US | disclosed |
| EP-2185713-B1 | PROCESS FOR PREPARING CHIRAL COMPOUNDS | PFIZER PROD INC (US) | 2014-09-10 | — | — | EP | disclosed |
| EP-2532660-B1 | Process for preparing chiral compounds | PFIZER PROD INC (US) | 2014-09-10 | — | — | EP | disclosed |
| US-20140187794-A1 | Process for Preparing Chiral Compounds | PFIZER INC. (US) | 2014-07-03 | — | — | US | disclosed |
| US-8642783-B2 | Process for preparing chiral compounds | PFIZER INC. (US) | 2014-02-04 | — | — | US | disclosed |
| EP-2576686-A1 | ELECTRONIC DEVICE MODULE COMPRISING FILM OF HOMOGENEOUS POLYOLEFIN COPOLYMER AND ADHESIVE PROPERTY ENHANCING GRAFT POLYMER | Dow Global Technologies LLC (US) | 2013-04-10 | — | — | EP | disclosed |
| EP-2576639-A1 | ELECTRONIC DEVICE MODULE COMPRISING FILM OF HOMOGENEOUS POLYOLEFIN COPOLYMER AND GRAFTED SILANE | Dow Global Technologies LLC (US) | 2013-04-10 | — | — | EP | disclosed |
| EP-2532660-A1 | Synthetic intermediates prepared using a 2-deoxyribose-5-phosphate aldolase (DERA) chemoenzymatic process | Pfizer Products Inc. (US) | 2012-12-12 | — | — | EP | disclosed |
| US-20110118476-A1 | Process for Preparing Chiral Compounds | PFIZER INC. | 2011-05-19 | — | — | US | disclosed |
| EP-2185713-A2 | PROCESS FOR PREPARING CHIRAL COMPOUNDS | Pfizer Products Inc. (US) | 2010-05-19 | — | — | EP | disclosed |
| US-20090221839-A1 | Preparation of an Atorvastatin Intermediate | PFIZER INC. | 2009-09-03 | — | — | US | disclosed |
| EP-1922315-B1 | PREPARATION OF AN ATORVASTATIN INTERMEDIATE | PFIZER SCIENCE & TECH LTD (IE) | 2009-05-27 | — | — | EP | disclosed |
| WO-2009019561-A2 | PROCESS FOR PREPARING CHIRAL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2009-02-12 | — | — | WO | disclosed |
| EP-1922315-A1 | PREPARATION OF AN ATORVASTATIN INTERMEDIATE | Pfizer Science and Technology Ireland Limited (IE) | 2008-05-21 | — | — | EP | disclosed |
| WO-2007029216-A1 | PREPARATION OF AN ATORVASTATIN INTERMEDIATE | PFIZER SCIENCE AND TECHNOLOGY IRELAND LIMITED (IE) | 2007-03-15 | — | — | WO | disclosed |