Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12330002 | 0.92 | ELANE (0.61) | ELANECYP2C9CYP3A4 | |
| SCHEMBL233472 | 0.87 | ELANE (0.63) | ELANECYP2C9CYP3A4 | |
| SCHEMBL231909 | 0.83 | ELANE (0.64) | ELANECYP2C9CYP3A4 | |
| SCHEMBL12329665 | 0.81 | ELANE (0.69) | ELANECYP2C9CYP3A4 | |
| SCHEMBL231215 | 0.81 | ELANE (0.60) | ELANECYP2C9CYP3A4 | |
| SCHEMBL15456549 | 0.80 | ELANE (0.58) | ELANECYP2C9CYP3A4 | |
| SCHEMBL230716 | 0.80 | ELANE (0.58) | ELANECYP2C9CYP3A4 | |
| SCHEMBL2742382 | 0.79 | ELANE (0.71) | ELANECYP2C9CYP3A4 | |
| SCHEMBL15456106 | 0.78 | ELANE (0.57) | ELANECYP2C9CYP3A4 | |
| SCHEMBL12330070 | 0.78 | ELANE (0.65) | ELANECYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2545057-B1 | PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF RESPIRATORY DISEASES SUCH AS COPD | CHIESI FARM SPA (IT) | 2017-06-07 | — | — | EP | disclosed |