Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10322934 | 0.81 | MEN1 (0.58) | MEN1KMT2ACYP2C19CYP1A2RAB9A | |
| SCHEMBL10322933 | 0.79 | HDAC8 (0.56) | MEN1KMT2ACYP2C19CYP1A2RAB9A | |
| SCHEMBL8987867 | 0.78 | MEN1 (0.78) | MEN1KMT2ACYP2C19CYP1A2RAB9A | |
| SCHEMBL13947380 | 0.77 | MEN1 (0.72) | MEN1KMT2ACYP2C19CYP1A2RAB9A | |
| SCHEMBL25872270 | 0.77 | MEN1 (0.72) | MEN1KMT2ACYP2C19CYP1A2RAB9A | |
| SCHEMBL6077374 | 0.76 | EPHX2 (0.80) | MEN1KMT2ACYP2C19CYP1A2RAB9A | |
| SCHEMBL2832296 | 0.75 | MAPT (0.72) | MEN1KMT2ACYP2C19CYP1A2RAB9A | |
| SCHEMBL5333738 | 0.75 | TSHR (0.66) | MEN1KMT2ACYP2C19CYP1A2RAB9A | |
| SCHEMBL10321777 | 0.75 | EPHX2 (0.61) | MEN1KMT2ACYP2C19CYP1A2RAB9A | |
| SCHEMBL18773661 | 0.75 | CA1 (0.67) | MEN1KMT2ACYP2C19CYP1A2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781661-B1 | VASOPRESSIN V1A ANTAGONISTS | VANTIA LTD (GB) | 2017-06-07 | — | — | EP | claimed |