Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GRK6 | P43250 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5542189 | 0.79 | GAA (0.56) | GAAMEN1KMT2AMAPTNPC1 | |
| SCHEMBL10224642 | 0.79 | GAA (0.69) | GAAMEN1KMT2AGRK6MAPT | |
| SCHEMBL13565572 | 0.77 | GAA (0.55) | GAAMEN1KMT2AGRK6MAPT | |
| SCHEMBL993415 | 0.77 | GAA (0.55) | GAAMEN1KMT2AGRK6MAPT | |
| SCHEMBL17876424 | 0.77 | GAA (0.55) | GAAMEN1KMT2AGRK6MAPT | |
| SCHEMBL23188417 | 0.77 | GAA (0.59) | GAAMEN1KMT2AGRK6MAPT | |
| SCHEMBL5542180 | 0.77 | GAA (0.55) | GAAMEN1KMT2AGRK6MAPT | |
| SCHEMBL805061 | 0.77 | MEN1 (0.71) | GAAMEN1KMT2AMAPTNPC1 | |
| SCHEMBL993416 | 0.77 | GRK6 (0.64) | GAAMEN1KMT2AGRK6MAPT | |
| SCHEMBL24251892 | 0.77 | GAA (0.51) | GAAMEN1KMT2AGRK6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669032-B2 | Enhanced treatment regimens using mTOR inhibitors | INTELLIKINE LLC (US) | 2017-06-06 | — | — | US | disclosed |