Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 20/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20681857 | 1.00 | MME (0.44) | MMEACE | |
| SCHEMBL21351243 | 0.91 | MME (0.45) | MMEACE | |
| SCHEMBL19788067 | 0.91 | MME (0.45) | MMEACE | |
| SCHEMBL19331567 | 0.90 | MME (0.46) | MMEACE | |
| SCHEMBL19331564 | 0.90 | MME (0.46) | MMEACE | |
| SCHEMBL15472737 | 0.90 | MME (0.46) | MMEACE | |
| Hydrochloric Acid SCHEMBL19376905 | 0.90 | MME (0.45) | MMEACE | |
| SCHEMBL19788074 | 0.88 | MME (0.45) | MMEACE | |
| SCHEMBL19687852 | 0.88 | MME (0.45) | MMEACE | |
| SCHEMBL19687938 | 0.88 | MME (0.41) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670186-B2 | Neprilysin inhibitors | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2017-06-06 | — | — | US | disclosed |