Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 19/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15623191 | 1.00 | CHRM1 (0.48) | CHRM1CHRM5CHRM2CHRM4ALDH1A1 | |
| SCHEMBL15630183 | 0.86 | CHRM1 (0.47) | CHRM1CHRM5CHRM2CHRM4 | |
| SCHEMBL15618492 | 0.83 | CHRM1 (0.45) | CHRM1CHRM5CHRM2CHRM4 | |
| SCHEMBL14978786 | 0.83 | CHRM1 (0.70) | CHRM1CHRM2CHRM4ALDH1A1 | |
| SCHEMBL15618674 | 0.82 | CHRM1 (0.46) | CHRM1CHRM5CHRM2CHRM4 | |
| SCHEMBL15618571 | 0.81 | CHRM1 (0.68) | CHRM1CHRM5CHRM2CHRM4 | |
| SCHEMBL20901308 | 0.79 | CHRM1 (0.47) | CHRM1CHRM5CHRM2CHRM4 | |
| SCHEMBL15618702 | 0.78 | CHRM1 (0.70) | CHRM1CHRM5CHRM2CHRM4 | |
| SCHEMBL20901247 | 0.76 | CHRM1 (0.41) | CHRM1CHRM5CHRM2CHRM4 | |
| SCHEMBL21597926 | 0.74 | CHRM1 (0.63) | CHRM1CHRM5CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669013-B2 | Bicyclic aza compounds as muscarinic M1 receptor agonists | HEPTARES THERAPEUTICS LIMITED (GB) | 2017-06-06 | — | — | US | disclosed |