Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 16/20 | 0.72 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18109496 | 0.91 | TLR8 (0.87) | TLR8TLR7KCNH2 | |
| SCHEMBL18109493 | 0.91 | TLR8 (0.87) | TLR8TLR7KCNH2 | |
| SCHEMBL18109695 | 0.89 | TLR8 (0.70) | TLR8TLR7KCNH2 | |
| SCHEMBL18109621 | 0.89 | TLR8 (0.70) | TLR8TLR7KCNH2 | |
| SCHEMBL18109622 | 0.89 | TLR8 (0.70) | TLR8TLR7KCNH2 | |
| SCHEMBL18109692 | 0.89 | TLR8 (0.70) | TLR8TLR7KCNH2 | |
| SCHEMBL18124772 | 0.87 | TLR8 (0.61) | TLR8TLR7KCNH2 | |
| SCHEMBL18109517 | 0.85 | TLR8 (0.65) | TLR8TLR7KCNH2 | |
| SCHEMBL18109514 | 0.85 | TLR8 (0.65) | TLR8TLR7KCNH2 | |
| SCHEMBL18109269 | 0.85 | TLR8 (0.65) | TLR8TLR7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670205-B2 | Toll like receptor modulator compounds | GILEAD SCIENCES, INC. (US) | 2017-06-06 | — | — | US | disclosed |