Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 11/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 11/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | IL1B | P01584 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.33 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19889409 | 0.85 | DDB1 (0.43) | DDB1CRBNMAP1LC3BTNFIL1B | |
| SCHEMBL20609671 | 0.83 | DDB1 (0.50) | DDB1CRBNMAP1LC3BMEN1KMT2A | |
| SCHEMBL19889425 | 0.81 | DDB1 (0.53) | DDB1CRBNTMEM97TNFIL1B | |
| SCHEMBL14294751 | 0.81 | DDB1 (0.45) | DDB1CRBNTMEM97HTR2ASIGMAR1 | |
| SCHEMBL14294754 | 0.79 | DDB1 (0.44) | DDB1CRBNTMEM97HTR2ASIGMAR1 | |
| SCHEMBL14294758 | 0.79 | DDB1 (0.45) | DDB1CRBNMAP1LC3BMEN1KMT2A | |
| SCHEMBL19889406 | 0.79 | DDB1 (0.42) | DDB1CRBNTMEM97HTR2ASIGMAR1 | |
| SCHEMBL14294755 | 0.79 | DDB1 (0.42) | DDB1CRBNTMEM97HTR2ASIGMAR1 | |
| SCHEMBL14294764 | 0.79 | DDB1 (0.42) | DDB1CRBNTMEM97HTR2ASIGMAR1 | |
| SCHEMBL14294737 | 0.79 | DDB1 (0.42) | DDB1CRBNTMEM97HTR2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669015-B2 | Piperidine-2, 6-dione derivatives and their use as tumor necrosis factor inhibitors | TIANJIN HEMAY BIO-TECH CO., LTD. (CN) | 2017-06-06 | — | — | US | disclosed |