Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19750123 | 0.82 | KMT2A (0.52) | KMT2ACYP2D6HRH3MEN1HSD11B1 | |
| SCHEMBL327725 | 0.82 | KMT2A (0.52) | KMT2ACYP2D6HRH3MEN1HSD11B1 | |
| SCHEMBL5990231 | 0.82 | KMT2A (0.52) | KMT2ACYP2D6HRH3MEN1HSD11B1 | |
| SCHEMBL61193 | 0.82 | — | — | |
| SCHEMBL2107485 | 0.82 | — | — | |
| SCHEMBL24793465 | 0.82 | KMT2A (0.52) | KMT2ACYP2D6HRH3MEN1HSD11B1 | |
| SCHEMBL6506975 | 0.82 | — | — | |
| SCHEMBL11435054 | 0.82 | KMT2A (0.52) | KMT2ACYP2D6HRH3MEN1HSD11B1 | |
| SCHEMBL944 | 0.82 | — | — | |
| SCHEMBL14218704 | 0.82 | KMT2A (0.52) | KMT2ACYP2D6HRH3MEN1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670165-B2 | SIK inhibitor for use in a method of treating an inflammatory and/or immune disorder | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-06-06 | — | — | US | disclosed |