Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 20/20 | 0.72 |
| ▸ | MAOA | P21397 | 6/20 | 0.72 |
| ▸ | MAOB | P27338 | 4/20 | 0.72 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18923917 | 0.85 | KDM1A (0.64) | KDM1AMAOAMAOB | |
| SCHEMBL16009812 | 0.84 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL16009813 | 0.84 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL29357857 | 0.84 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL14882283 | 0.84 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL14882286 | 0.84 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL16010056 | 0.84 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL16009931 | 0.84 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL16010546 | 0.84 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL29357936 | 0.84 | KDM1A (1.00) | KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670136-B2 | (Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors | ORYZON GENOMICS S.A. (ES) | 2017-06-06 | — | — | US | disclosed |