Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.46 |
| ▸ | MAOA | P21397 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1637914 | 0.74 | HTR2A (0.44) | MAOBMAOAHTR2AOPRM1 | |
| SCHEMBL15222949 | 0.74 | HTR2A (0.45) | MAOBMAOAHTR2AOPRM1 | |
| Hydrochloric Acid SCHEMBL16398669 | 0.72 | MAOB (0.45) | MAOBMAOAHTR2AOPRM1 | |
| SCHEMBL1071202 | 0.70 | HTR2A (0.41) | HTR2AOPRM1 | |
| SCHEMBL8468669 | 0.70 | DPP4 (0.46) | MAOBMAOA | |
| SCHEMBL19992871 | 0.69 | MAOB (0.48) | MAOBMAOAOPRM1 | |
| SCHEMBL19717526 | 0.69 | MAOB (0.62) | MAOBMAOAHTR2AOPRM1 | |
| SCHEMBL415543 | 0.69 | SLC6A4 (0.47) | OPRM1 | |
| SCHEMBL15819350 | 0.67 | HTR2A (0.59) | MAOBMAOAHTR2AOPRM1 | |
| SCHEMBL24481549 | 0.67 | HTR2A (0.67) | HTR2AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670136-B2 | (Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors | ORYZON GENOMICS S.A. (ES) | 2017-06-06 | — | — | US | disclosed |