SCHEMBL18924161

SCHEMBL18924161

NC(=O)C(N)CCCCNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.64

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.64
EPHX2 P34913 1/20 0.45
DPP8 Q6V1X1 3/20 0.43
DPP7 Q9UHL4 3/20 0.43
ANPEP P15144 1/20 0.42
TLR2 O60603 2/20 0.41
DPP4 P27487 2/20 0.41
DPP9 Q86TI2 2/20 0.41
CASP3 P42574 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29482146 0.96 KMT2A (0.62) KMT2AEPHX2DPP8DPP7TLR2
SCHEMBL2089280 0.91 KMT2A (0.67) KMT2AEPHX2DPP8DPP7ANPEP
SCHEMBL29401369 0.91 KMT2A (0.67) KMT2AEPHX2DPP8DPP7ANPEP
SCHEMBL29679073 0.91 KMT2A (0.67) KMT2AEPHX2DPP8DPP7ANPEP
SCHEMBL10052316 0.91 KMT2A (0.67) KMT2AEPHX2DPP8DPP7ANPEP
SCHEMBL16379394 0.91 KMT2A (0.64) KMT2AEPHX2DPP8DPP7ANPEP
SCHEMBL29398504 0.91 KMT2A (0.67) KMT2AEPHX2DPP8DPP7ANPEP
SCHEMBL16379396 0.91 KMT2A (0.64) KMT2AEPHX2DPP8DPP7ANPEP
SCHEMBL29401202 0.91 KMT2A (0.67) KMT2AEPHX2DPP8DPP7ANPEP
SCHEMBL13160289 0.91 KMT2A (0.67) KMT2AEPHX2DPP8DPP7ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9671400-B2 Conjugate molecules DAKO DENMARK A/S (DK) 2017-06-06 US disclosed