Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 17/20 | 0.46 |
| ▸ | FER | P16591 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20750864 | 1.00 | SYK (0.46) | SYKFER | |
| SCHEMBL9106559 | 0.92 | SYK (0.55) | SYKFER | |
| SCHEMBL5027829 | 0.89 | SYK (0.44) | SYKFER | |
| SCHEMBL20750755 | 0.89 | SYK (0.42) | SYKFER | |
| SCHEMBL18925384 | 0.89 | SYK (0.42) | SYKFER | |
| SCHEMBL9102097 | 0.86 | SYK (0.49) | SYK | |
| SCHEMBL18925389 | 0.85 | SYK (0.46) | SYKFER | |
| SCHEMBL18925885 | 0.85 | SYK (0.49) | SYKFER | |
| SCHEMBL20750824 | 0.84 | SYK (0.60) | SYKFER | |
| SCHEMBL18925566 | 0.84 | SYK (0.60) | SYKFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3176154-A1 | BENZAMIDES AND NICOTINAMIDES AS SYK MODULATORS | Portola Pharmaceuticals, Inc. (US) | 2017-06-07 | — | — | EP | disclosed |