Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 16/20 | 0.47 |
| ▸ | FER | P16591 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5027980 | 0.91 | SYK (0.57) | SYKFER | |
| SCHEMBL20473635 | 0.91 | SYK (0.57) | SYKFER | |
| SCHEMBL18925761 | 0.88 | SYK (0.49) | SYKFER | |
| SCHEMBL18925674 | 0.87 | SYK (0.59) | SYKFER | |
| SCHEMBL18925374 | 0.84 | SYK (0.49) | SYKFER | |
| SCHEMBL18925293 | 0.83 | SYK (0.52) | SYKFER | |
| SCHEMBL20750735 | 0.82 | FER (0.44) | SYKFER | |
| SCHEMBL18926102 | 0.82 | SYK (0.48) | SYKFER | |
| SCHEMBL18926021 | 0.81 | FER (0.49) | SYKFER | |
| SCHEMBL20750789 | 0.81 | FER (0.49) | SYKFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3176154-B1 | BENZAMIDES AND NICOTINAMIDES AS SYK MODULATORS | PORTOLA PHARM INC (US) | 2019-02-20 | — | — | EP | disclosed |
| EP-3176154-A1 | BENZAMIDES AND NICOTINAMIDES AS SYK MODULATORS | Portola Pharmaceuticals, Inc. (US) | 2017-06-07 | — | — | EP | disclosed |