Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9948332 | 0.77 | BACE1 (0.42) | BACE1APP | |
| SCHEMBL9948333 | 0.77 | BACE1 (0.42) | BACE1APP | |
| SCHEMBL1824234 | 0.62 | PBRM1 (0.52) | BACE1APP | |
| SCHEMBL3124444 | 0.62 | PBRM1 (0.52) | BACE1APP | |
| SCHEMBL7968965 | 0.62 | PBRM1 (0.52) | BACE1APP | |
| SCHEMBL16105864 | 0.62 | PBRM1 (0.52) | BACE1APP | |
| SCHEMBL18289345 | 0.61 | PBRM1 (0.33) | BACE1APP | |
| SCHEMBL9882194 | 0.60 | PBRM1 (0.31) | — | |
| SCHEMBL9931593 | 0.60 | PBRM1 (0.31) | — | |
| SCHEMBL9931594 | 0.60 | PBRM1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3176172-A1 | SPIROIMIDAZOLE COMPOUNDS AND THEIR USE AS BACE INHIBITORS | Astrazeneca AB (SE) | 2017-06-07 | — | — | EP | disclosed |