Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9947776 | 1.00 | BACE1 (0.57) | BACE1APP | |
| SCHEMBL9947773 | 1.00 | BACE1 (0.57) | BACE1APP | |
| SCHEMBL9948520 | 0.90 | BACE1 (0.51) | BACE1APP | |
| SCHEMBL9948387 | 0.87 | BACE1 (0.53) | BACE1APP | |
| SCHEMBL9948090 | 0.87 | BACE1 (0.59) | BACE1APP | |
| SCHEMBL9948093 | 0.87 | BACE1 (0.59) | BACE1APP | |
| SCHEMBL9948210 | 0.86 | BACE1 (0.59) | BACE1APP | |
| SCHEMBL9948462 | 0.86 | BACE1 (0.59) | BACE1APP | |
| SCHEMBL10250210 | 0.84 | BACE1 (0.51) | BACE1APP | |
| SCHEMBL9948255 | 0.84 | BACE1 (0.61) | BACE1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3176172-A1 | SPIROIMIDAZOLE COMPOUNDS AND THEIR USE AS BACE INHIBITORS | Astrazeneca AB (SE) | 2017-06-07 | — | — | EP | disclosed |