Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9948253 | 0.86 | BACE1 (1.00) | BACE1APP | |
| SCHEMBL9948256 | 0.86 | BACE1 (1.00) | BACE1APP | |
| SCHEMBL21654395 | 0.84 | BACE1 (0.65) | BACE1APP | |
| SCHEMBL21654350 | 0.77 | BACE1 (0.60) | BACE1APP | |
| SCHEMBL21654422 | 0.77 | BACE1 (0.73) | BACE1APP | |
| SCHEMBL9948505 | 0.76 | BACE1 (1.00) | BACE1APP | |
| SCHEMBL9948501 | 0.76 | BACE1 (1.00) | BACE1APP | |
| SCHEMBL9948667 | 0.76 | BACE1 (1.00) | BACE1APP | |
| SCHEMBL18926449 | 0.74 | BACE1 (0.63) | BACE1APP | |
| SCHEMBL18561440 | 0.74 | BACE1 (0.74) | BACE1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3176172-A1 | SPIROIMIDAZOLE COMPOUNDS AND THEIR USE AS BACE INHIBITORS | Astrazeneca AB (SE) | 2017-06-07 | — | — | EP | disclosed |