Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 2/20 | 0.87 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.87 |
| ▸ | PDE4A | P27815 | 18/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2472569 | 1.00 | PDE1A (0.87) | PDE1APDE1BPDE4A | |
| SCHEMBL14243419 | 0.93 | PDE1A (1.00) | PDE1APDE1BPDE4A | |
| SCHEMBL14243117 | 0.92 | PDE1A (1.00) | PDE1APDE1BPDE4A | |
| SCHEMBL12198194 | 0.92 | PDE1A (0.74) | PDE1APDE1BPDE4A | |
| SCHEMBL18927849 | 0.91 | PDE4A (1.00) | PDE1APDE1BPDE4A | |
| SCHEMBL2507601 | 0.91 | PDE4A (1.00) | PDE1APDE1BPDE4A | |
| SCHEMBL14243423 | 0.90 | PDE4A (0.85) | PDE1APDE1BPDE4A | |
| SCHEMBL14158310 | 0.90 | PDE4A (0.85) | PDE1APDE1BPDE4A | |
| SCHEMBL29790189 | 0.90 | PDE4A (0.85) | PDE1APDE1BPDE4A | |
| SCHEMBL12198217 | 0.88 | PDE4A (0.82) | PDE1APDE1BPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367429-B1 | ORGANIC COMPOUNDS | INTRA CELLULAR THERAPIES INC (US) | 2017-06-07 | — | — | EP | disclosed |