Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PTPRB | P23467 | 8/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15432495 | 1.00 | ABCB1 (0.54) | ABCB1CA1CA2CA7CA4 | |
| SCHEMBL13108147 | 1.00 | ABCB1 (0.54) | ABCB1CA1CA2CA7CA4 | |
| SCHEMBL24140388 | 0.91 | ABCB1 (0.67) | ABCB1CA1CA2CA7PTPRB | |
| SCHEMBL24140416 | 0.91 | ABCB1 (0.67) | ABCB1CA1CA2CA7PTPRB | |
| SCHEMBL28923528 | 0.91 | ABCB1 (0.67) | ABCB1CA1CA2CA7PTPRB | |
| SCHEMBL15947604 | 0.90 | ABCB1 (0.50) | ABCB1CA1CA2CA7CA4 | |
| SCHEMBL20800061 | 0.90 | ABCB1 (0.50) | ABCB1CA1CA2CA7CA4 | |
| SCHEMBL15947618 | 0.87 | ABCB1 (0.41) | ABCB1CA1CA2CA9PTPRB | |
| SCHEMBL15433017 | 0.85 | ABCB1 (0.53) | ABCB1CA1CA2CA7CA4 | |
| SCHEMBL18928619 | 0.85 | ABCB1 (0.53) | ABCB1CA1CA2CA7CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872157-B1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | HANGZHOU DAC BIOTECH CO LTD (CN) | 2020-01-22 | — | — | EP | disclosed |
| US-10399941-B2 | Conjugates of cell binding molecules with cytotoxic agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2019-09-03 | — | — | US | disclosed |
| US-20180021448-A9 | Conjugates of Cell Binding Molecules with Cytotoxic Agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2018-01-25 | — | — | US | disclosed |
| US-20170296663-A1 | Conjugates of Cell Binding Molecules with Cytotoxic Agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2017-10-19 | — | — | US | disclosed |
| US-20170157262-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10399941-B2 | Conjugates of cell binding molecules with cytotoxic agents | CD4, CD2, CD47 | ABCB1 944/4885CA1 2258/4885CA2 4016/4885 |
| US-20170157262-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | CD4, CD2, CD47 | ABCB1 973/4885CA1 2346/4885CA2 3901/4885 |
| US-20180021448-A9 | Conjugates of Cell Binding Molecules with Cytotoxic Agents | CD4, CD2, CD47 | ABCB1 944/4885CA1 2258/4885CA2 4016/4885 |
| US-20170296663-A1 | Conjugates of Cell Binding Molecules with Cytotoxic Agents | CD4, CD2, CD47 | ABCB1 944/4885CA1 2258/4885CA2 4016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.