Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18919894 | 0.93 | NR1I2 (0.51) | NR1I2 | |
| SCHEMBL18920114 | 0.93 | NR1I2 (0.51) | NR1I2 | |
| SCHEMBL18919893 | 0.93 | NR1I2 (0.51) | NR1I2 | |
| SCHEMBL18928454 | 0.89 | NR1I2 (0.43) | NR1I2 | |
| SCHEMBL18928387 | 0.88 | NR1I2 (0.42) | NR1I2 | |
| SCHEMBL18928217 | 0.86 | NR1I2 (0.50) | NR1I2 | |
| SCHEMBL18928370 | 0.86 | NR1I2 (0.44) | NR1I2 | |
| SCHEMBL18928326 | 0.85 | NR1I2 (0.43) | NR1I2 | |
| SCHEMBL18928382 | 0.84 | NR1I2 (0.42) | NR1I2 | |
| SCHEMBL18928176 | 0.84 | NR1I2 (0.45) | NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017093938-A1 | TETRAHYDROISOQUINOLINE DERIVATIVES | VIIV HEALTHCARE UK LIMITED (GB) | 2017-06-08 | — | — | WO | disclosed |