Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 20/20 | 0.63 |
| ▸ | EDNRB | P24530 | 18/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.63 |
| ▸ | TSPO | P30536 | 1/20 | 0.63 |
| ▸ | DRD3 | P35462 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19569100 | 0.90 | EDNRA (0.64) | EDNRAEDNRBSLC6A2TSPODRD3 | |
| SCHEMBL12973800 | 0.89 | EDNRA (0.78) | EDNRAEDNRBSLC6A2TSPODRD3 | |
| SCHEMBL18929688 | 0.88 | EDNRA (0.76) | EDNRAEDNRBSLC6A2TSPODRD3 | |
| SCHEMBL18330569 | 0.83 | EDNRA (0.81) | EDNRAEDNRBSLC6A2TSPODRD3 | |
| SCHEMBL22404283 | 0.81 | EDNRA (0.54) | EDNRAEDNRBSLC6A2TSPODRD3 | |
| SCHEMBL18929883 | 0.81 | EDNRA (0.52) | EDNRAEDNRBSLC6A2TSPODRD3 | |
| SCHEMBL22404009 | 0.81 | EDNRA (0.54) | EDNRAEDNRBSLC6A2TSPODRD3 | |
| SCHEMBL8267995 | 0.80 | EDNRA (0.71) | EDNRAEDNRBSLC6A2TSPODRD3 | |
| SCHEMBL22404331 | 0.80 | EDNRA (0.56) | EDNRAEDNRBSLC6A2TSPODRD3 | |
| SCHEMBL22504780 | 0.79 | EDNRA (0.52) | EDNRAEDNRBSLC6A2TSPODRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017093903-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF MACITENTAN | LAURUS LABS PRIVATE LIMITED (IN) | 2017-06-08 | — | — | WO | disclosed |